Image:COX-2 inhibited by Aspirin.png

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Summary

Description

Structure of COX-2 (also called prostaglandin H synthase) inactivated by aspirin. The molecule is a dimer, the blue and green halves are identical. In each monomer, the active site serine has been acetylated, inactivating it. Also visible in each monomer is the salicylic acid from which the acyl group came, and the heme cofactor.

Source

self-made, release to public domain

Date

9-7-2007

Author

Jeff Dahl

Permission
( Reusing this image)

see below


Licensing

Public domain
I, the copyright holder of this work, hereby release it into the public domain. This applies worldwide.

In case this is not legally possible:
I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.


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File history

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Date/Time Thumbnail Dimensions User Comment
current 19:46, 7 September 2007 Thumbnail for version as of 19:46, 7 September 2007 3,560×2,235 (1.19 MB) Jeff Dahl ({{Information |Description=Structure of COX-2 (also called prostaglandin H synthase) inactivated by aspirin. The molecule is a dimer, the blue and green halves are identical. In each monomer, the active site serine has been acetylated, inactivating it. Al)
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